Clinical Utilities
Detect antibodies directed at phospholipid epitopes.

CPT Codes

Reference Range
IgG <16 EIA units
IgM <22 EIA units
IgA <10 EIA units

Component Information

Name		CARDIOLIPIN IGG AUTOANTIBODIES
Method		EIA
CPT Code		86147
Units		GPL U/mL
Ref Range		Less than 12
Reflex Reason

Name		CARDIOLIPIN IGM AUTOANTIBODIES
Method		EIA
CPT Code		86147
Units		MPL U/mL
Ref Range		Less than 11
Reflex Reason

Name		CARDIOLIPIN IGA AUTOANTIBODIES
Method		EIA
CPT Code		86147
Units		APL U/mL
Ref Range		Less than 13
Reflex Reason

Name		PHOSPHATIDYLSERINE IGG AUTOANTIBODIES
Method		EIA
CPT Code		86148
Units		EIA UNITS
Ref Range		Less than 16
Reflex Reason

Name		PHOSPHATIDYLSERINE IGM AUTOANTIBODIES
Method		EIA
CPT Code		86148
Units		EIA UNITS
Ref Range		Less than 22
Reflex Reason

Name		PHOSPHATIDYLSERINE IGA AUTOANTIBODIES
Method		EIA
CPT Code		86148
Units		EIA UNITS
Ref Range		Less than 20
Reflex Reason

Name		BETA-2-GLYCOPROTEIN I IGG AUTOANTIBODIES
Method		EIA
CPT Code		86146
Units		U/mL
Ref Range		Les than 20
Reflex Reason

Name		BETA-2-GLYCOPROTEIN I IGM AUTOANTIBODIES
Method		EIA
CPT Code		86146
Units		U/mL
Ref Range		Less than 10
Reflex Reason

Name		BETA-2-GLYCOPROTEIN I IGA AUTOANTIBODIES
Method		EIA
CPT Code		86146
Units		U/mL
Ref Range		Less than 10
Reflex Reason

Name		DRVVT SCREEN
Method		CLOT DETECTION
CPT Code		85613
Units		Seconds
Ref Range		<41.0
Reflex Reason

Name		DRVVT MIXING STUDY
Method		CLOT DETECTION
CPT Code
Units		Seconds
Ref Range		<40
Reflex Reason

Name		DRVVT CONFIRM
Method		CLOT DETECTION
CPT Code
Units		Seconds
Ref Range
Reflex Reason

Name		DRVVT RATIO
Method		CALC
CPT Code
Units
Ref Range		<1:20
Reflex Reason

Name		DRVVT INTERPRETATION
Method		CLOT DETECTION
CPT Code
Units
Ref Range		Negative
Reflex Reason

Collection Notes
1. Draw a plain red top tube to remove tissue fluid contamination.
Pour off serum into plastic tube and label tube "Serum". 
2. Draw blood into a buffered citrate collection tube (light blue 
top) filled to proper level.  Sodium citrate of 0.105M or 0.129M
should be used.  Use of other anticoagulants may cause invalid 
results.
3. Gently invert 6 times to mix.  Process immediately.
4. Centrifuge the capped tube at 1500 x g (platelet poor) for 15 
minutes to obtain platelet-poor plasma.
5. Remove plasma using a plastic transfer pipette.
6. Repeat centrifugation at 1500 x g for 15 minutes to assure
complete platelet removal.
7. Dispense the plasma into 2 plastic tubes using plastic pipet.  
Label tube "plasma".
8. Freeze immediately at -70 C.
9. Specimen must remain frozen at all times.  SSpecialty 
within 24 hours on dry ice.

Additional Comments
Heparin concentrations greater than 1 U/mL can cause false-positive results; thus, heparinized plasma is not acceptable.