Clinical Utilities
Used in the diagnosis of beta thalassemia sickling disorders, common structural hemoglobinapthies such as Hb S, C, E, D-Punjab, Lepore etc. It is also used in evaluating infants following abnormal newborn screening. Some forms of alpha-thalassemias are readily identified by HPLC e.g. when Hb Barts, Hb H, and/or Hb Constant Spring are observed. However, alpha-thalassemias resulting from only 1 or 2 alpha-globin gene deletion/nonfunction are not recognized in adults. Fortunately the majority (approximately 85-90%) of alpha thalassemia carriers have commonly encountered deletions which are identified in Alpha Thalassemia DNA Mutation Analysis. Rarer forms of alpha thalassemia (point mutations and small insertion/deletions) can be detected by Alpha-Globin Complete.

CPT Codes
83021, 85014, 85018, 85041 Any Hemoglobin S result >0.1% will automatically reflex to Sickle Cell Screen (QVAL test code 4986) for an additional fee (add CPT code 85660).

The CPT codes provided are based on AMA guidelines
and are for informational purposes only. CPT coding is the
sole responsibility of the billing party. Please direct any questions
regarding coding to the payer being billed.

Reference Range
An Interpretive Report is Provided.

Component Information