MULTIPLE SCLEROSIS (MS) PROFILE
Marquette General Health System

General Info

HLAB/HOL Code

  MSE

MGH LIS Test No

  868

Schedule

  Monday - Saturday

Testing Time

   

Testing Lab

  Mayo Labs

QORR Test Code

  MSE

Specimen Info

Type

  Serum and CSF  

Volume

  1 mL each

Temperature

  Refrigerate

Preservative

   

Collection Info

  Serum and spinal fluid are required for this test. 

Spinal fluid must be obtained within 1 week of serum draw.

Serum
Draw blood in a plain, red-top tube(s) or a serum gel tube(s). 
Spin down and send 1 mL of serum refrigerated.
Note:    Label specimen appropriately (serum).  

Spinal Fluid
1 mL of spinal fluid. Send specimen refrigerated.
Note:     Label specimen appropriately (spinal fluid). 
 
Specimen Acceptability

Methods
Isoelectric Focusing (IEF) with IgG Immunoblot Detection Nephelometry

Clinical Utilities
Useful in the diagnosis of MS. Especially helpful in patients with equivocal clinical or radiological findings.

CPT Codes
82040/Albumin, serum 82042/Albumin, spinal fluid 82784/x2 IgG, serum and spinal fluid 83916/Oligoclonal band, spinal fluid 83916/Oligoclonal band, serum (if appropriate)

The CPT codes provided are based on AMA guidelines
and are for informational purposes only. CPT coding is the
sole responsibility of the billing party. Please direct any questions
regarding coding to the payer being billed.

Reference Range
OLIGOCLONAL BANDS
<4 bands

CSF INDEX

CSF IgG index: 0.00-0.85
CSF IgG: 0.0-8.1 mg/dL
CSF albumin: 0.0-27.0 mg/dL
Serum IgG 

0-4 months: 100-334 mg/dL
5-8 months: 164-588 mg/dL
9-14 months: 246-904 mg/dL
15-23 months: 313-1,170 mg/dL
2-3 years: 295-1,156 mg/dL
4-6 years: 386-1,470 mg/dL
7-9 years: 462-1,682 mg/dL
10-12 years: 503-1,719 mg/dL
13-15 years: 509-1,580 mg/dL
16-17 years: 487-1,327 mg/dL
> or =18 years: 767-1,590 mg/dL

Serum albumin: 3,200-4,800 mg/dL
CSF IgG/albumin: 0.0-0.21
Serum IgG/albumin: 0.0-0.4
CSF IgG synthesis rate: 0-12 mg/24 hours

Component Information

Collection Notes

Additional Comments

 

Questions or Comments email support@mgh.org

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