FISH ANALYSIS LYMPHOMA PANEL
Marquette General Health System
HLAB/HOL Code |
CYTGNREQ. | |
MGH LIS Test No |
1384 | |
Schedule |
Monday - Friday | |
Testing Time |
2-5 Days | |
Testing Lab |
Marquette General Hospital | |
QORR Test Code |
CYTGNREQ. | |
Type |
See Collection Info | |
Volume |
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Temperature |
Ambient | |
Preservative |
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Collection Info |
Bone Marrow. Malignant Blood, Fresh Tissue, Paraffin Embedded Tissue 3.0 mL Bone Marrow 5.0 mL Blood Obtain 1 cm(3) of fresh tissue Tissue specimen fixed in 10% neutral buffered formalin paraffin-embedded block (FFPET). Ambient Bone marrow: sodium heparin Whole blood: sodium heparin Fresh Tissue: Hank's balanced salt solution (HBBS), Ringer's solution or normal saline FFPET: 10% neutral buffered formalin Bone marrow/Whole blood: Draw into sodium heparin (green-top) tube(s), invert several times to mix (clotted specimens can compromise results). Maximum time from collection should be 24 hours. Fresh tissue: Place specimen in a screw-capped, sterile container with sterile HBBS, Ringer's solution or normal saline. Please send the specimen immediately after resection. Specimen must reach the laboratory within 24 hours if time is delayed send specimen refrigerated. FFPET: Specimen must be fixed in 10% neutral buffered formalin fixed paraffin-embedded tissue block. Optimum fixation time 12-24 hrs but not to exceed 48 hrs or be less than 6 hrs. Maintain the specimen at room temperature. Do not freeze. Please provide: (1) Pathology Report (2) H & E of the fixed specimen. Region of invasive carcinoma marked by a pathologist on the H & E. Limitations or Unacceptable Conditions: Specimen fixed in fixative other than 10% neutral buffered formalin or decalcified. Label specimen containers with the patient's name and a unique identifying number (MGHS encounter # or MR #). SPECIMENS CANNOT BE FROZEN |
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Clinical Utilities
Detection of abnormalities involving ALK, BCL6, MYC, IGH,
t(8;14), t(11;14), t(11;18), and t(14;18) most commonly
associated with B cell lymphoma.
CPT Codes
Bone Marrow/Whole Blood
88271 x 17 DNA probe,each
88275 x 9 Interphase in situ Hybridization (technical)
88291x1 Interpretation and Reporting (professional)
As needed CPT codes (additional charge):
88237- Cell Culture-BM/Malignant Blood
Fresh Tissue/Lymph Node:
88271 x 17 DNA probe,each
88275 x 6 Interphase in situ Hybridization (technical)
88291x1 Interpretation and Reporting (professional)
As needed CPT codes (additional charge):
88239- Tissue culture for neoplastic disorders; solid tumor
Paraffin Embedded Tissue:
88368 Morphometric Analysis, each probe (global)
As needed CPT Codes (additional charge):
88387 Macroscopic examination of fresh tissue for molecular analysis (professional)
88363 Archived tissue for molecular analysis (professional)
The CPT codes provided are based on AMA guidelines
and are for informational purposes only. CPT coding is the
sole responsibility of the billing party. Please direct any questions
regarding coding to the payer being billed.
Reference Range
An interpretive report will be provided.
Component Information
Additional Comments Questions or Comments email support@mgh.org
Reference Lab Home Page
Laboratory Main Page
Marquette General Health System Home Page