FISH ANALYSIS, MULTIPLE MYELOMA PANEL
Marquette General Health System

General Info

HLAB/HOL Code

   CYTGREQ.

MGH LIS Test No

   5446

Schedule

   Monday - Friday

Testing Time

   4-7 Days

Testing Lab

   Marquette General Hospital

QORR Test Code

   CYTGREQ.

Specimen Info

Type

   Bone Marrow or Malignant Blood  

Volume

   3.0 mL of BM or 5.0 mL of Blood

Temperature

   Ambient or Refrigerated

Preservative

   Green-Top (Na Heparin)

Collection Info

   Prefer a minimum of 3.0 mL of bone marrow or 
5.0 mL of malignant blood.  Draw into green-top
(sodium heparin) tube (s), invert several times to 
mix (clotted specimens may not work and can
compromise results.)  Label vial with patient's name
and a unique identifying number.  Maximum time
from collection should be 24 hrs.

SPECIMENS CANNOT BE FROZEN
 
Specimen Acceptability

Methods
Interphase set-up and analysis of 200 cells for BAP IGH, 13q-, 17p-, CEN 3/CEN 7; and CEN 9 /CEN 15; 500 cells for CCND1/IGH FGFR3/IGH, and IGH/MAF fusion.

Clinical Utilities
Detection of abnormalities invloving 13q/-13, 14q, 17p, CEN 3/CEN 7, CEN9/cen 15, t(4;14), t(11;14) or t (14;16) translocations most commonly associated with multiple myeloma or MGUS.

CPT Codes
88271 x 16 DNA probe, each 88275 x 9 Interphase in situ Hybridization 88291 x 8 Interpretation and Reporting Additional as needed: 88237 Cell Culture-BM/Malignant Blood

Reference Range
An interpretive report will be provided.

Component Information

Collection Notes

Additional Comments

 

Questions or Comments email support@mgh.org

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