FISH ANALYSIS IGH/CCND1
Marquette General Health System

General Info

Alpha Code

  CYTOGNREQ

MGH LIS Test No

   

Schedule

  Monday - Friday

Testing Time

  1-2 Days

Testing Lab

  Marquette General Hospital

QORR Test Code

  CYTOGNREQ

Specimen Info

Type

  Bone Marrow or Malignant Blood  

Volume

  3.0 mL Bone Marrow or 5.0 mL Blood

Temperature

  Ambient

Preservative

   

Collection Info

  Prefer a minimum of 3.0 mLof bone
marrow or 5.0 mL of malignant blood.
Draw into green-top (sodium-heparin)
tube(s), invert several times to mix.  
Clotted specimens may not work and
can compromise results.  Label vial
with patient's name and a unique 
identifying number (MGH encounter
# or MR #).  Maximum time from collection
should be 24 hrs.

SPECIMENS CANNOT BE FROZEN
 
Specimen Acceptability

Methods
Interphase set-up and analysis. A minimum of 500 interphase nuclei will be analyzed.

Clinical Utilities
Diagnosis of IGH-CCND1gene fusion characteristic of the t(11;14)(q13;q32) most commonly associated with mantle cell lymphoma or multiple myeloma.

CPT Codes
88271x2 (DNA probe, each), 88275x2 (Interphase in situ hybridization), 88291 (Interpretation and Reporting). The following CPT's are added at additional charge when needed: 88230 (Cell culture- lymphocytes).

Reference Range
0-0.6 % fusion = Normal
Above 0.6% fusion = Abnormal

Component Information

Collection Notes

Additional Comments

 

Questions or Comments email support@mgh.org

Reference Lab Home Page
Laboratory Main Page
Marquette General Health System Home Page