FISH ANALYSIS BCR/ABL
Marquette General Health System
HLAB/HOL Code |
CYTOGNREQ | |
MGH LIS Test No |
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Schedule |
Monday-Friday | |
Testing Time |
1-2 Days | |
Testing Lab |
Marquette General Hospital | |
QORR Test Code |
FISHBC | |
Type |
Bone Marrow or Malignant Blood | |
Volume |
3.0 mL Bone Marrow or 5.0 mL Blood | |
Temperature |
Ambient | |
Preservative |
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Collection Info |
Bone Marrow is the tissue of choice for initial diagnosis of most neoplastic specimens. Malignant blood can be used in certain cases to monitor minimal residual disease. Prefer a minimum of 3.0 mL of bone marrow or 5.0 mL of malignant blood. Draw into green-top (sodium heparin) tube(s), invert several times to mix (clotted specimens may not work and can compromise results). Label vial with the patient's name and a unique identifying number (MGHS encounter # or MR #). Maximum time from collection should be 24 hours. SPECIMENS CANNOT BE FROZEN |
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Clinical Utilities
Diagnosis of BCR-ABL gene fusion
characteristic of the Philadelphia
chromosome (Ph) associated
with t(9;22)(q34;q11.2)
CPT Codes
88271x2 (DNA probe, each), 88275x2 (Interphase in situ hybridization), 88291 (Interpretation and reporting). The following CPT codes are added at additional charge as needed: 88237 (Cell culture, lymphocytes), 88271x1 (DNA probe, each), 88275x2 (Interphase in situ hybridization) if additional cells required.
The CPT codes provided are based on AMA guidelines
and are for informational purposes only. CPT coding is the
sole responsibility of the billing party. Please direct any questions
regarding coding to the payer being billed.
Reference Range
0-0.6% fusion = Normal
Above 0.6% fusion = Abnormal
Component Information
Additional Comments Questions or Comments email support@mgh.org
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