FISH ANALYSIS AP12/MALT1
Marquette General Health System
Alpha Code |
CYTOGNREQ | |
MGH LIS Test No |
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Schedule |
Monday - Friday | |
Testing Time |
1-2 Days | |
Testing Lab |
Marquette General Hospital | |
QORR Test Code |
FISHAP | |
Type |
Bone Marrow or Malignant Blood | |
Volume |
3.0 mL Bone Marrow or 5.0 mL Blood | |
Temperature |
Ambient | |
Preservative |
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Collection Info |
Bone Marrow is the tissue of choice for initial diagnosis of most neoplastic specimens. Malignant blood can be used in certain cases to monitor minimal residual disease. Prefer a minimum of 3.0 mL of bone marrow or 5.0 mL of malignant blood. Draw into green-top (sodium heparin) tube(s), invert several times to mix (clotted specimens may not work and can compromise results). Label vial with the patient's name and a unique identifying number (MGHS encounter # or MR #). Maximum time from collection should be 24 hours. SPECIMENS CANNOT BE FROZEN |
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Clinical Utilities
Diagnosis of API2-MALT1 gene fusion
characteristic of t(11;18)(q21;q21)
associated with marginal zone B-cell
lymphoma of Mucosa-Associated
Lymphoid Tissue (MALT).
CPT Codes
88271x2 (DNA probe, each), 88275x2 (Interphase in situ hybridization), 88291 (interpretation and reporting). The following CPT codes are added at additional charge when needed: 88230 (Cell culture, lymphocytes).
Reference Range
0-0.6% Fusion = Normal
Above 0.6% fusion = Abnormal
Component Information
Additional Comments Questions or Comments email support@mgh.org
Reference Lab Home Page
Laboratory Main Page
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