CHROMOSOME ANALYSIS, HEMATOLOGIC, BLOOD
Marquette General Health System

General Info

HLAB/HOL Code

  CYTOGNREQ

MGH LIS Test No

   

Schedule

  Monday-Friday

Testing Time

  5-7 Days

Testing Lab

  Marquette General Hospital

QORR Test Code

  CHRBL

Specimen Info

Type

  1 Green Top (Sodium Heparin)  

Volume

  5.0 mL of Malignant Whole Blood

Temperature

  Ambient

Preservative

   

Collection Info

  Note:  Bone Marrow is the tissue of choice for 
initial diagnosis of most neoplastic specimens.  
For Bone Marrow testing information please 
see " Chromosome Analysis, Hematologic, Bone 
Marrow" in the test directory.

Studies on malignant blood can be informative 
in advanced stages of disease where abnormal 
cells have infiltrated to peripheral blood.  Generally,
chromosome analysis will be successful if greater 
than 10 % blasts are present.

Draw blood into green-top (sodium heparin) tube(s),
invert several times to mix.  Clotted specimens may 
not work and can compromise results.  Other 
anticoagulants may be harmful to the viability of the 
cells.  Label vial with patient's name and a unique
identifying number (MGHS encounter #, or MR#).  
Maximum time from collection should be 24 hours.

SPECIMENS CANNOT BE FROZEN.
 
Specimen Acceptability

Methods
Includes GTG banding, analysis of 20 or more metaphases, and karyograms for each cell line. Further studies, including FISH techniques, may be necessary.

Clinical Utilities
Chromosome analysis is useful for the diagnosis and classification of certain malignant hematological disorders, evaluatingthe prognosis in patients with certain malignant hematological disorders, monitoring the effects of treatment, and monitoring patients in remission.

CPT Codes
88237(tissue culture), 88264(chromosome analysis, 20-25 cells), 88291(Report and Interpretation). The following CPT codes may be added at additional charge if needed: 88280 (additional karyotypes), 88285 (additional cells), 88261 (STAT analysis; 5 cells and 1 karyotype).

The CPT codes provided are based on AMA guidelines
and are for informational purposes only. CPT coding is the
sole responsibility of the billing party. Please direct any questions
regarding coding to the payer being billed.

Reference Range
46,XX or 46XY.  No apparent abnormality.

Component Information

Collection Notes

Additional Comments

 

Questions or Comments email support@mgh.org

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