Y CHROMOSOME MICRODELETIONS, MOLECULAR DETECTION

Y CHROMOSOME MICRODELETIONS, MOLECULAR DETECTION
Marquette General Health System

General Info

Alpha Code		Y2844
MGH LIS Test No		2844
Schedule		Monday Thorugh Friday
Testing Time		14 Days
Testing Lab		Mayo Labs
QORR Test Code		Y2844

Specimen Info

Type		EDTA Whole Blood in Orig. Vacutainer(s)
Volume		5.0 mL
Temperature		Ambient
Preservative
Collection Info		"Molecular Genetics - Congenital Inherited Diseases Patient Information Sheet" (Supply T521) is required for all orders. If not ordering electronically, please submit the above information sheet along with a "Molecular Genetics Request Form" (Supply T245) with the specimen. Specimen must arrive within 96 hours of draw. Draw blood in a lavender-top (EDTA) tube(s) or a yellow-top (ACD) tube(s), and send 5.0 mL of EDTA or ACD whole blood in original VACUTAINER(S). Invert several times to mix blood. Forward unprocessed whole blood promptly at ambient temperature.

Type		ACD Whole Blood in Orig. Vacutainer(s)
Volume		5.0 mL
Temperature		Ambient
Preservative
Collection Info		"Molecular Genetics - Congenital Inherited Diseases Patient Information Sheet" (Supply T521) is required for all orders. If not ordering electronically, please submit the above information sheet along with a "Molecular Genetics Request Form" (Supply T245) with the specimen. Specimen must arrive within 96 hours of draw. Draw blood in a lavender-top (EDTA) tube(s) or a yellow-top (ACD) tube(s), and send 5.0 mL of EDTA or ACD whole blood in original VACUTAINER(S). Invert several times to mix blood. Forward unprocessed whole blood promptly at ambient temperature.

Specimen Acceptability

Ambient/Refrigerated OK/Frozen No

Specimen Retention Time= 3 Months (whole blood, extracted DNA
stored Frozen)

Methods
Direct Mutation Analysis by PCR

Clinical Utilities
Evaluating men with azoospermia, severe oligozoospermia, or otherwise unexplained male factor infertility.

CPT Codes
83890, 83894X2, 83900

Reference Range
Abnormal: the presence of 1 or more deletions in specific regions of the Y chromosome (designated AZFa, AZFb, and AZFc)

Normal: the absence of deletions in the Y chromosome under test.

*An interpretive report will indicate whether or not results are consistent with a diagnosis of Y chromosome microdeletion.

Component Information

Collection Notes
Additional Comments

Questions or Comments email support@mgh.org

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