Clinical Utilities
Recurrent bacterial infections, particularly of the skin, subcutaneous areas, or regional lymph nodes are a frequent presenting complaint of patients with defects in neutrophil function (e.g., chronic granulomatous disease). Sinopulmonary infections are also common. While most patients with recurrent infections have normal neutrophils, a persistent infection that fails to respond to appropriate medical treatment or infection with an organism that is unusual in an otherwise normal host suggest a possible neutrophil function defect. Normal neutrophil function is dependent on a number of properties including migration toward the site of infection, phagocytosis, and microbicidal activity. Measuring the neutrophil oxidative burst indirectly assesses microbicidal activity.

CPT Codes
88180x2

Reference Range
Normal

Component Information