CHROMOSOME ANALYSIS, AUTOPSY, STILLBIRTH OR PRODUCTS OF CONCEPTION
Marquette General Health System

General Info

Alpha Code

   C8044

MGH LIS Test No

   8044

Schedule

   Monday through Sunday

Testing Time

   21 Days

Testing Lab

   Mayo Labs

QORR Test Code

   C8044

Specimen Info

Type

      

Volume

    

Temperature

   Refrigerate

Preservative

    

Collection Info

   AUTOPSY
Obtain a 1.0 cm(3) biopsy specimen of muscle/fascia from the thigh.
Place the specimen in a sterile, screw-capped container with sterile
Hank's balanced salt solution, Ringer's solution, or normal saline.
(Hank's balanced salt solution [Supply T132] is supplied by Mayo 
Medical Laboratories.) Do not handle with hands. Label container with 
patient's name and laboratory control number.  Send specimen 
refrigerated. (Keep specimen cool with frozen coolant
April-October. Protect specimen from freezing by placing it in a
bubble-pack bag [Supply T055] supplied by Mayo Medical Laboratories.
Use refrigerated coolant November-March). SPECIMEN CANNOT BE FROZEN.  
Promptly mail by Priority Mail to Mayo Medical Laboratories.
NOTE:  Please complete a "Cytogenetics/AFP Congenital Disorders
       Request Form" (Supply T238) and forward it with the specimen.  
       This form is supplied by Mayo Medical Laboratories.
 
PRODUCTS OF CONCEPTION OR STILLBIRTH
Obtain a 1.0 cm(3) biopsy specimen of muscle/fascia from the thigh 
and about 1.0 cm(3) of placenta (including chroionic villi). If a 
fetus cannot be specifically identified, collect villus material or
tissue that appears to be of fetal origin. Do not handle with hands.
Place each specimen in a screw-capped, sterile container with Hank's
balanced salt solution, Ringer's solution, or normal saline. (Hank's
balanced salt solution [Supply T132] is supplied by Mayo Medical
Laboratories.) Do not handle with hands. Label each container with
the specimen type (e.g., placenta), patients name, and laboratory
control number. Send specimen refrigerated. (Keep specimen cool with
frozen coolant April-October. Protect specimen from freezing by
placing it in a bubble-pack bag [Supply T055] supplied by Mayo Medical
Laboratories. Use refrigerated coolant November-March). SPECIMEN CANNOT
BE FROZEN. Promptly mail by Priority Mail to Mayo Medical Laboratories.
NOTE:  Please complete a "Cytogenetics/AFP Congenital Disorders
       Request Form" (Supply T238) and forward it with the specimen.
       This form is supplied by Mayo Medical Laboratories.      
 
Specimen Acceptability

Methods
AUTOPSY Includes 2-banded karyotypes, analysis of 20 or more metaphases, and other techniques when required. STILLBIRTH OR PRODUCTS OF CONCEPTION Includes 2-banded karyotypes, analysis of 20 or more metaphases, and other techniques when required. Due to bacterial contamination or nonviable cells, these specimens fail about 25% of the time. Because there is a problem with maternal cell contamination, please attempt to identify and send fetal tissue for chromosome analysis.

Clinical Utilities

CPT Codes
88262/chromosome analysis, autopsy, stillbirth or products /of conception 88233/tissue culture for chromosome analysis 88291/Interpretation and report.

Reference Range
46,XX or 46,XY.  No apparent chromosome abnormality.
Photograph of the representative karyotype.      

Component Information

Collection Notes

Additional Comments

 

Questions or Comments email support@mgh.org

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