CUTANEOUS IMMUNOFLUORESCENCE, BIOPSY
Marquette General Health System
HLAB/HOL Code |
CUTBX | |
MGH LIS Test No |
8394 | |
Schedule |
Monday through Friday | |
Testing Time |
1 day | |
Testing Lab |
Mayo Labs | |
QORR Test Code |
C8394 | |
Type |
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Volume |
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Temperature |
Media-Amb\Refr OK\No media-Frozen | |
Preservative |
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Collection Info |
Punch biopsy (4 mm) of uninvolved or involved skin as per complete instructions. Skin or mucosal specimens can be sent by using either the transport medium or the snap-frozen procedure. The practical value of using transport medium (supplied by Mayo Medical Laboratories) is recognized for direct immunofluorescence testing. However, we have found a loss in sensitivity of approximately 10% with the transport medium as compared with snap-frozen tissue. This may necessitate a repeat biopsy if the result seems to be false-negative. The assay cannot be performed on specimens fixed in formalin. TRANSPORT MEDIUM METHOD Immediately drop specimen into provided vial of transport medium. Seal tightly. SNAP-FROZEN METHOD 1. Immediately drop specimen into liquid nitrogen and allow to freeze thoroughly (do not allow specimen to desiccate). If liquid nitro- gen is not available, the specimen may be frozen by placing it on a small square of aluminum foil on a block of dry ice. The former is preferred. 2. Immediately wrap specimen carefully in aluminum foil. At no time should the specimen be allowed to thaw. Wrap as you would a party favor or a piece of taffy candy. 3. Place the wrapped specimen into the prelabeled plastic vial and seal tightly. 4. Send specimen frozen on dry ice. NOTE: 1. BIOPSY SITE, WHETHER THE BIOPSY WAS OBTAINED FROM SUN-EXPOSED VERSUS UNEXPOSED SKIN, WHETHER IT IS FROM PERILESIONAL, INVOLVED, OR UNINVOLVED SKIN, AND DATE OF COLLECTION ARE REQUIRED ON REQUEST FORM FOR PROCESSING. 2. Please complete a "Pathology/Dermatology/Cytology Request Form"and forward it with the specimen. This form is supplied by Mayo Medical Laboratories. Requisitions for this procedure cannot be processed unless the information requested is supplied. |
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Clinical Utilities CPT Codes Reference Range
88323/cutaneous immunofluorescence, biopsy
88346/x5 direct immunofluorescence staining
The CPT codes provided are based on AMA guidelines
and are for informational purposes only. CPT coding is the
sole responsibility of the billing party. Please direct any questions
regarding coding to the payer being billed.
Report includes description and interpretation of staining patterns.
Component Information
Additional Comments Questions or Comments email support@mgh.org
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