CEREBROSPINAL FLUID (CSF) IGG INDEX

CEREBROSPINAL FLUID (CSF) IGG INDEX
Marquette General Health System

General Info

HLAB/HOL Code		CSFIG
MGH LIS Test No		9934
Schedule		Monday through Saturday
Testing Time		Same day/1 Day
Testing Lab		Mayo Labs
QORR Test Code		CSFIG

Specimen Info

Type
Volume
Temperature		Refrigerate
Preservative
Collection Info		Serum and spinal fluid are required. Specimens must be obtained within 1 week of each other. Serum Container/Tube: Plain, red-top tube(s) or serum gel tube(s) Specimen Volume: 1 mL of serum Collection Instructions: Note: Label specimen appropriately (serum). Spinal Fluid Container/Tube: Sterile vial(s) Specimen Volume: 1 mL of spinal fluid Collection Instructions: Note: Label specimen appropriately (spinal fluid). Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected. Serum: 0.5 mL Spinal Fluid: 0.5 mL

Specimen Acceptability

Methods
The cerebrospinal fluid (CSF) and serum IgG and albumin are determined by immunonephelometry on a Siemens Nephelometer II. The CSF IgG index and synthesis rate are calculated and reported. In addition, the serum IgG and albumin, CSF IgG and albumin, and serum and CSF IgG/albumin ratios are reported. (Instruction manual: Siemens Nephelometer II Operations. Siemens, Inc., Newark, DE)
Clinical Utilities
CPT Codes
82040-Albumin, serum 82042-Albumin, spinal fluid 82784 x 2-IgG, serum and spinal fluid

The CPT codes provided are based on AMA guidelines
and are for informational purposes only. CPT coding is the
sole responsibility of the billing party. Please direct any questions
regarding coding to the payer being billed.
Reference Range
CSF index: 0.00-0.85
CSF IgG: 0.0-8.1 mg/dL
CSF albumin: 0.0-27.0 mg/dL

Serum IgG
0-4 months: 100-334 mg/dL
5-8 months: 164-588 mg/dL
9-14 months: 246-904 mg/dL
15-23 months: 313-1,170 mg/dL
2-3 years: 295-1,156 mg/dL
4-6 years: 386-1,470 mg/dL
7-9 years: 462-1,682 mg/dL
10-12 years: 503-1,719 mg/dL
13-15 years: 509-1,580 mg/dL
16-17 years: 487-1,327 mg/dL
> or =18 years: 767-1,590 mg/dL

Serum albumin: 3,200-4,800 mg/dL
CSF IgG/albumin: 0.00-0.21
Serum IgG/albumin: 0.0-0.4
CSF IgG synthesis rate: 0-12 mg/24 hours

Component Information
Collection Notes
Additional Comments

Questions or Comments email support@mgh.org

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