COAGULATION FACTOR IX INHIBITOR SCREEN, PLASMA
Marquette General Health System

General Info

Alpha Code

   FAC9I

MGH LIS Test No

   575

Schedule

   Varies

Testing Time

   1 day

Testing Lab

   Mayo Labs

QORR Test Code

   FAC9I

Specimen Info

Type

      

Volume

    

Temperature

   Frozen

Preservative

    

Collection Info

   See special instructions on "Coagulation Studies."
 
1. Draw blood in light blue-top (citrate) tube(s).  Spin down, remove
   plasma, spin plasma again, and place 2.0 mL of citrate platelet-
   poor plasma into 2 plastic vials each containing 1.0 mL.  (Glass
   vials cannot be accepted.)
   NOTE:  A. Specimen must be collected prior to factor replacement
             therapy.
          B. Double-centrifuged specimens are critical for accurate
             results as platelet contamination may cause spurious
             results.
2. Draw blood in light blue-top (citrate) tube(s) as a control specimen
   from a normal, unrelated person at the same time.  Spin down, remove
   plasma, spin plasma again, and place 2.0 mL of citrate platelet-poor
   plasma into 2 plastic vials each containing 1.0 mL.  Label clearly
   on outermost label NORMAL CONTROL.
   NOTE:  Double-centrifuged specimens are critical for accurate
          results as platelet contamination may cause spurious results.
3. Freeze patient and control specimens immediately at < or = -40
   degrees C, if possible.
4. Send patient and control specimens frozen on dry ice in the same
   shipping container.
   NOTE:  Each coagulation assay requested should have its own
          separate set of patient and control vials.
5. If priority specimen, mark requisition, give reason, and request
   a call-back.
NOTE:  Please complete a "Coagulation Request Form" and forward it
       with the specimen.  This form is supplied by Mayo Medical
       Laboratories.  Requisitions for this procedure cannot be
       processed unless the information requested is supplied.      
 
Specimen Acceptability

Methods
Indicate specific factor requested. Includes factor activity assay for the specified factor. Useful for detection and titering of coagulation inhibitor to the specific factor requested, primarily factor IX in patients with hemophilia A or B. NOTE: If type of inhibitor is unknown, see "Coagulation Consultation, Lupus-Like Anticoagulant/Circulating Anticoagulant, Plasma."

Clinical Utilities

CPT Codes
85335, 85610, 85670, 85635, 85732, 85730, 85613, 85348, 85597

Reference Range
Adults:  65-140%
 
Normal full-term newborn infants or healthy premature inafants
may have decreased levels ( > or = 20%) which may not reach adult
levels for > or = 180 days postnatal.
 
INHIBITOR SCREEN
Negative      

Component Information

Collection Notes

Additional Comments

 

Questions or Comments email support@mgh.org

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