Clinical Utilities

CPT Codes
83520

Reference Range
<4.0 Units ...........IgG Not Detected
>=4.0 Units..........IgG Detected

Some multiple slcerosis patients receiving recombinant
interferon-beta develop IFNB-specific antibodies that may
block the therapeutic effect of the treatment.  This assay 
screens for IgG antibodies capable of binding to IFNB; all 
samples with detectable IFNB binding antibodies are then
tested for INFB neutralizing antibodies using a biaoassay.
Approximately two weeks are required to perform the 
neutralization bioassay; those results will be reported 
separately when available.

*Neutralizing AB is done at additional charge.

Component Information

Name		INTERFERON BETA IGG AUTOANTIBODIES
Method		MAID
CPT Code		83520
Units		U/mL
Ref Range		<4.0 Units ...........IgG Not Detected >=4.0 Units..........IgG Detected
Reflex Reason

Collection Notes

Additional Comments
This test includes antibodies to both interferon Beta 1a and 1b.