CATECHOLAMINES, FRACTIONATED 24 HOUR URINE
Marquette General Health System

General Info

HLAB/HOL Code

  CATU

MGH LIS Test No

  606

Schedule

  Tuesday - Saturday

Testing Time

  2-4 Days

Testing Lab

  Quest Valencia

QORR Test Code

  CATU

Specimen Info

Type

  Urine - 24 hr collection  

Volume

  30.0 (15.0) mL aliqout

Temperature

  Frozen - 2 Month(s),Refrigerated - 7 Day(s)

Preservative

   

Collection Info

  If possible, patient should discontinue all drugs at least 1 week prior to collection. 
Medications known to interfere with this assay include: Alpha-methyldopa (Aldomet), 
Isoproterenol, Labetalol, Mandelamine, Metaclopramide, Acetaminophen (high concentrations 
only), Cimetidine, and Catecholamine-containing drugs, MAO inhibitors, diuretics, 
vasodilators. Other interfering substances include smoking and drinking tea 
within 4 hours of collecting specimen. 1. Refrigerate during and after collection. 
2. Record the 24hr total volume on the requesition form or shipping manifest. 
3. Store and ship refrigerated. 
 
Specimen Acceptability

Methods
HPLC

Clinical Utilities
Evaluate hypertension, especially if paroxysmal; evaluate orthostatic hypotension; diagnose pheochromocytoma; preoperative evaluation of suspected childhood adrenal neoplasms (i.e., neuroblastoma); evaluate possible multiple endocrine adenomatosis. Slightly elevated concentrations (100-200 ug/24 hr) of urinary free catecholamines are consistent with essential hypertension; elevated concentrations (>200 ug/24 hr) are suggestive of pheochromocytoma. Further confirmation of elevated urinary catecholamines can be obtained by determination of urinary metanephrines.

CPT Codes
82384

The CPT codes provided are based on AMA guidelines
and are for informational purposes only. CPT coding is the
sole responsibility of the billing party. Please direct any questions
regarding coding to the payer being billed.

Reference Range
Catecholamines Total (E+NE) 24 hr Ur            < 100 ug/24hr   
Epinephrine 24 hr Urine                   < 20 ug/24hr   
Norepinephrine 24 hr Urine                < 80 ug/24hr   
Dopamine 24 hr Urine                < 500 ug/24hr  

Component Information

Name

  TOTAL (E PLUS NE) 

Method

  HPLC 

CPT Code

  82384 

Units

  mcg/24hr 
Ref Range   Less than 100 
Reflex Reason    
     

Name

  EPINEPHRINE 

Method

  HPLC 

CPT Code

   

Units

  mcg/24hr 
Ref Range   Less than 20 
Reflex Reason    
     

Name

  NOREPINEPHRINE 

Method

  HPLC 

CPT Code

   

Units

  mcg/24hr 
Ref Range   Less than 80 
Reflex Reason    
     

Name

  DOPAMINE 

Method

  HPLC 

CPT Code

   

Units

  mcg/24hr 
Ref Range   Less than 500 
Reflex Reason    
     

Name

  TOTAL URINE VOLUME 

Method

   

CPT Code

   

Units

  mL 
Ref Range    
Reflex Reason    
     
Collection Notes

Additional Comments

 

Questions or Comments email support@mgh.org

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